The Medicines Company Announces that the ORION-10 Study of Inclisiran in ASCVD Patients Showed Durable and Potent Lowering of LDL-C with Twice-Yearly Dosing
MEDICINES (MDCO)
Last medicines earnings: 10/30 07:00 am
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US:NASDAQ Investor Relations:
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Source: Business Wire
- Inclisiran achieved 58% LDL-C lowering with time-adjusted reductions of 56% sustained over 18 months of treatment in patients with atherosclerotic cardiovascular disease (ASCVD)- ORION-10 study affirmed inclisiran’s excellent safety profile, including no treatment-related liver or renal abnormalities- Results presented today during late-breaking science session at American Heart Association annual meeting in Philadelphia- The Medicines Company to host investor conference call and webcast on Monday, November 18, 12:00 pm EST PHILADELPHIA--(BUSINESS WIRE)--The Medicines Company (NASDAQ: MDCO) today announced detailed results from ORION-10, the second of three pivotal 18-month low-density lipoprotein cholesterol (LDL-C) lowering Phase 3 clinical studies of inclisiran, an investigational twice-yearly therapy to reduce LDL-C and the first and only cholesterol-lowering treatment in the siRNA (small-interfering RNA) class. In ORION-10, twice-yearly dosing with inclisiran sodium 300 mg m
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