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-0.012448132780083 -0.00456431535269707 -0.0103734439834025 -0.0093360995850623 -0.0155601659751037 -0.0143153526970954 -0.0454356846473029 -0.0632780082987551
Stock impact report

Medicines Co. shares rally 17% premarket on news of positive trial of cholesterol treatment [MarketWatch]

MEDICINES (MDCO) 
Last medicines earnings: 10/30 07:00 am Check Earnings Report
US:NASDAQ Investor Relations: themedicinescompany.com/investors
Company Research Source: MarketWatch
Medicines Co. shares rally 17% premarket on news of positive trial of cholesterol treatment The Medicines Co. shares MDCO, -2.40% rose 17% in premarket trade Tuesday, after the company said a late-stage trial of a cholesterol treatment met its main goals. The company said a Phase 3 trial of incliran, an investigational twice-yearly therapy to reduce low-density lipoprotein cholesterol, or LDL-C, and the first and only cholesterol-lowering therapy in the siRNA (small-interfering RNA or "sir-nah") class, met its primary and secondary endpoints and showed a strong safety profile. "The results of the ORION-11 trial support the unprecedented potential of inclisiran to deliver assurance to clinicians and patients that LDL-C can be lowered in a sustained fashion over the long-term with an infrequent dosing regimen and an excellent safety profile," said Kausik Ray, M.D., principal investigator on the trial, called Orion-11, and consultant cardiologist at Imperial College London. The trial Show less Read more
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