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0 0 0 0 0.00323624595469249 -0.000647249190938497 0.0045307443365696 0.000647249190938497
Stock impact report

Eli Lilly outlays $1.12bn for hearing loss gene therapy partnership [Yahoo! Finance]

MeiraGTx Holdings plc - Ordinary Shares (MGTX) 
Company Research Source: Yahoo! Finance
The partnership will see the two companies develop and commercialise programmable recombinase-based treatments targeting hearing loss indications. In exchange for using Seamless' recombinase platform, Lilly will pay the biotech over $1.12bn in an upfront payment and R&D funding. The exact breakdown of milestone payments and additional royalties on any approved drugs was not disclosed. Germany-based Seamless, which launched in 2023, uses programmable recombinases to address genetic diseases. Recombinases are specialised enzymes that catalyse site-specific DNA rearrangements, including excision, insertion, and translocation. These enzymes have been used in scientific research for decades, but only now are they being harnessed for the potential of commercialised therapies. The biotech says its platform can perform large but precise DNA edits along the genome, enabling treatment across a broad range of diseases. Following the deal with Lilly, Seamless will design and programme site-s Show less Read more
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