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Stock impact report

Eli Lilly signs deal for MeiraGTx's gene therapy for severe eye disease [Yahoo! Finance Canada]

MeiraGTx Holdings plc - Ordinary Shares (MGTX) 
Shares ?of the gene therapy developer rose 12.5% to $9.55 in premarket trading on Monday after the news. Under the deal, MeiraGTx will get an upfront payment of $75 million and potentially over $400 ?million more in milestone payments.? MeiraGTx is also eligible to receive tiered royalties on licensed products. This marks Lilly's latest effort to ?tap the market for eye treatments and bolster its focus on gene therapies, after signing a deal valued at up to $261.7 million to ?buy gene therapy developer Adverum Biotechnologies in October. Adverum is ?developing an eye injection for wet age-related macular degeneration, or wAMD, a leading cause of blindness among the elderly. MeiraGTx's experimental therapy, AAV-AIPL1, is being studied to treat one of the most severe forms of Leber congenital amaurosis 4, ?caused by mutations in the AIPL1 gene,? and is delivered via subretinal injection ?to children. Through a one-time administration, AAV-AIPL1 is designed to deliver functional Show less Read more
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