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0.000235031435454612 -0.00376050296727179 -0.00270286150772654 0.000881367882954379 0.00693342734590756 0.00141018861272701 0.00252658793113583 0.00364298724954465
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Enthorin Therapeutics Announces Initiation of Phase II Clinical Trial of MRM-3379 (Formerly ENT-3379) for Fragile X Syndrome by Licensing Partner Mirum Pharmaceuticals

Mirum Pharmaceuticals, Inc. - common stock (MIRM) 
Last mirum pharmaceuticals, inc. - common stock earnings: 3/12 04:02 pm Check Earnings Report
Company Research Source: Business Wire
ESCONDIDO, Calif.--(BUSINESS WIRE)--Enthorin Therapeutics, LLC, a biotechnology company focused on circuit-modulating treatments for neurological and neurodevelopmental disorders, announced that its licensing partner for MRM-3379 (formerly ENT-3379), Mirum Pharmaceuticals, Inc. (NASDAQ: MIRM), in December, reported the initiation of the BLOOM Phase 2 clinical study evaluating MRM-3379 in Fragile X syndrome (FXS).MRM-3379 is an orally available, highly brain-penetrant, selective phosphodiesterase-4D (PDE4D) inhibitor designed to enhance cAMP signaling. The compound was discovered by scientists at Dart Neuroscience (DNS), including current members of Enthorin Therapeutics, and advanced through Phase 1 clinical development at DNS. Preclinical data, including results from an FMR1 knockout mouse model of Fragile X syndrome, suggest that MRM-3379 improves cognition and alleviates behavioral deficits across multiple domains.The entry of MRM-3379 into Fragile X patient trials by Mirum Pha Show less Read more
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