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0.000776096235933212 7.76096235934756E-05 -0.00015521924718651 0.000776096235933212 0.00186263096623988 0.00294916569654634 0.0010089251067132 0.000278618548700024
Stock impact report

Jemperli contends with blockbuster Keytruda in endometrial cancer [Yahoo! Finance]

Merck & Company, Inc. (new) (MRK) 
Last merck & company, inc. (new) earnings: 4/28 06:45 am Check Earnings Report
US:NYSE Investor Relations: investors.merck.com/home/default.aspx
Company Research Source: Yahoo! Finance
with standard of care (SOC) chemotherapy for the treatment of adult patients with primary advanced or recurrent endometrial cancer, including those with mismatch repair proficient (MMRp)/microsatellite stable (MSS) status, which is a severely underserved patient population. The sBLA approval is based on the success of the Phase III RUBY Part I trial and places Jemperli in direct competition with Merck & Co's Keytruda (pembrolizumab), the blockbuster agent of the same immune checkpoint inhibitor (ICI) class. Jemperli is a monoclonal antibody targeting PD-1, an inhibitory immunological checkpoint receptor, which activates an anti-tumor immune response during cancer treatment. Jemperli has already been approved in combination with SOC chemotherapy, followed by Jemperli as monotherapy, for the treatment of recurrent or advanced endometrial cancer adult patients with mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) status. In the Phase III RUBY Part I trial, the Show less Read more
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