Merck's trial of KEYTRUDA regimen fails to meet primary endpoint [Yahoo! Finance]
Merck & Company, Inc. (new) (MRK)
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Source: Yahoo! Finance
high-risk endometrial cancer following surgery with curative intent, failed to meet its primary endpoint. Sponsored by Merck, the trial is being carried out in collaboration with the European Network for Gynecologic Oncology Trial (ENGOT) groups and the GOG Foundation. The randomised, double-blind study involved 1,095 patients to assess adjuvant treatment with KEYTRUDA plus chemotherapy, irrespective of radiotherapy status versus adjuvant placebo plus chemotherapy, with or without radiotherapy. The primary endpoints are disease-free survival (DFS) and overall survival (OS), and secondary endpoints include safety. According to the data from an interim analysis by an independent Data Monitoring Committee, KEYTRUDA regimen failed to show DFS improvement versus placebo. The secondary goal of OS was not tested due to the lack of superiority in DFS. KEYTRUDA's safety profile was in line with those in prior studies without any new safety signals detected. The comprehensive data
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MRK
Earnings
- 4/25/24 - Beat
MRK
Sec Filings
- 5/15/24 - Form 424B5
- 5/15/24 - Form POSASR
- 5/6/24 - Form 144
- MRK's page on the SEC website