Phanes Therapeutics signs clinical supply agreement with Roche [Yahoo! Finance]
Merck & Company, Inc. (new) (MRK)
Last merck & company, inc. (new) earnings: 4/28 06:45 am
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Source: Yahoo! Finance
The collaboration will focus on evaluating PT217, Phanes' first-in-class bispecific antibody, in combination with Roche's atezolizumab, an anti-programmed death-ligand 1 (PD-L1) therapy. The study aims to treat various forms of neuroendocrine carcinomas and small cell lung cancer (SCLC). It will assess the efficacy of PT217 combined with atezolizumab in treating large-cell neuroendocrine carcinoma of the lung (LCNEC), and extrapulmonary neuroendocrine carcinomas (EP-NECs). Recently, the US Food and Drug Administration (FDA) granted fast-track designation to PT217 for treating patients with extensive-stage small cell lung cancer (ES-SCLC) with disease progression following platinum chemotherapy. Phanes is currently enrolling subjects in the multi-centre Phase I SKYBRIDGE study. It aims to assess the safety, preliminary efficacy, tolerability and pharmacokinetics of PT217 in advanced or refractory cancers expressing delta-like canonical Notch ligand 3 (DLL3). The study's next
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MRK
Earnings
- 4/25/24 - Beat
MRK
Sec Filings
- 5/15/24 - Form 424B5
- 5/15/24 - Form POSASR
- 5/6/24 - Form 144
- MRK's page on the SEC website