Merck Provides Update on Phase 3 KEYNOTE-B21 Trial Evaluating KEYTRUDA® (pembrolizumab) Plus Chemotherapy, With or Without Radiotherapy, for Patients With Newly Diagnosed, High-Risk Endome...
Merck & Company, Inc. (new) (MRK)
Last merck & company, inc. (new) earnings: 4/28 06:45 am
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Source: Business Wire
RAHWAY, N.J.--(BUSINESS WIRE)--Merck (NYSE: MRK), known as MSD outside of the United States and Canada, today announced that the Phase 3 KEYNOTE-B21 trial evaluating KEYTRUDA, Merck’s anti-PD-1 therapy, in combination with chemotherapy as adjuvant treatment, with or without radiotherapy, did not meet its primary endpoint of disease-free survival (DFS) for the treatment of patients with newly diagnosed, high-risk endometrial cancer after surgery with curative intent.At a pre-specified interim analysis conducted by an independent Data Monitoring Committee, adjuvant treatment with KEYTRUDA plus chemotherapy, with or without radiotherapy, did not meet the study’s pre-specified statistical criteria for DFS compared to placebo plus adjuvant chemotherapy, with or without radiotherapy. The study’s other primary endpoint of overall survival (OS) was not formally tested since superiority was not reached for DFS. The safety profile of KEYTRUDA was consistent with that observed in previously
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News
- A Deeper Look at Anti-PD-1/PD-L1 Checkpoint Inhibitors for Cancer [Forbes]Forbes
- Summit pares gains as ‘China-only' trial beats Merck's Keytruda [Seeking Alpha]Seeking Alpha
- Summit Shares Soar After Lung Cancer Drug Tops Keytruda in Study [Yahoo! Finance]Yahoo! Finance
- Summit Shares Soar After Lung Cancer Drug Tops Keytruda in Study [BNN Bloomberg (Canada)]BNN Bloomberg
- Summit lead asset beats Merck's Keytruda in a first in lung cancer [Seeking Alpha]Seeking Alpha
MRK
Earnings
- 4/25/24 - Beat
MRK
Sec Filings
- 5/30/24 - Form CERT
- 5/30/24 - Form 8-A12B
- 5/30/24 - Form 8-K
- MRK's page on the SEC website