First Clinical Outcomes Evaluating Six-Week Dosing Schedule for Merck’s KEYTRUDA® (pembrolizumab) Presented at AACR Virtual Annual Meeting I
Merck & Company, Inc. (new) (MRK)
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Source: Business Wire
Data Demonstrate Efficacy and Safety of KEYTRUDA 400 mg Every Six Weeks (Q6W) Comparable to Approved 200 mg Every Three Weeks (Q3W) Regimen Resubmitted Supplemental Biologics License Applications (sBLAs) for KEYTRUDA Q6W Dosing Under Review with US FDA Across All Approved Adult Indications KENILWORTH, N.J.--(BUSINESS WIRE)--Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced the presentation of interim data from Cohort B of KEYNOTE-555, a Phase 1 trial evaluating a 400 mg every six-week (Q6W) dosing regimen for KEYTRUDA, Merck’s anti-PD-1 therapy, in patients with metastatic melanoma. Results of the study – which represent the first clinical outcomes evaluating Q6W dosing for KEYTRUDA – demonstrated efficacy and safety comparable to findings from previous melanoma trials evaluating KEYTRUDA monotherapy. Interim data showed an overall response rate (ORR) of 38.6% (n=17/44) (95% CI, 24.4-54.5) in patients who received KEYTRUDA 400 mg Q6W, the primary
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