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-0.00333545108005081 -0.00333545108005081 -0.00285895806861503 -0.0065120711562897 -0.00333545108005081 -0.0470139771283356 -0.0549555273189328 -0.0509847522236341
Stock impact report

Marinus (MRNS) Down 83% on Lead Drug Falling Short in Seizure Study [Yahoo! Finance]

Marinus Pharmaceuticals, Inc. (MRNS) 
Last marinus pharmaceuticals, inc. earnings: 11/6 07:30 am Check Earnings Report
US:NASDAQ Investor Relations: ir.marinuspharma.com/investor-relations
Company Research Source: Yahoo! Finance
RAISE study evaluating lead drug ganaxolone in refractory status epilepticus (RSE). The RAISE study, which evaluated an intravenous (IV) formulation of ganaxolone, did not meet the pre-defined ‘stopping' criteria in RSE patients. While an independent data monitoring committee (IDMC) recommended continuing the RAISE study, management has decided to stop enrolling patients in the study of approximately 100 patients. A life-threatening condition, status epilepticus is marked by seizures that last longer than five minutes or more than one seizure within five minutes. Per management, the condition affects up to 150,000 patients every year in the United States alone. Patients with this condition who do not respond to first-line or second-line treatments are considered to have RSE. An oral formulation of ganaxolone has been approved in the United States since 2022 to treat seizures associated with CDKL5 deficiency disorder (CDD) in patients two years of age and older. This version of Show less Read more
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