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Stock impact report

Neurocrine Biosciences Announces Initiation of Phase 1 Clinical Study Evaluating Effects of NBI-1076986 in Healthy Adults [Yahoo! Finance]

Neurocrine Biosciences, Inc. (NBIX) 
Last neurocrine biosciences, inc. earnings: 2/4 04:05 pm Check Earnings Report
Company Research Source: Yahoo! Finance
clinical study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of investigational compound NBI-1076986 in healthy adult participants. NBI-1076986 is an investigational, oral, M4 subtype-selective muscarinic acetylcholine receptor antagonist for the potential treatment of movement disorders that was discovered and developed by Neurocrine Biosciences. "This compound is an important part of our muscarinic portfolio, which enters the clinic as a potential treatment for movement disorders," said Eiry W. Roberts, M.D., Chief Medical Officer at Neurocrine Biosciences. "Selectively targeting M4 receptors could benefit a broad range of motor coordination disorders, including Parkinson's disease tremor and dystonia." About Muscarinic Pipeline and NBI-1076986 Muscarinic receptors are fundamental to activating signaling pathways in the brain. There are five muscarinic acetylcholine receptors involved in neurotransmission (M1–M5), with M4 receptors associated with Show less Read more
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