NantKwest and ImmunityBio Present Results of Landmark Trial of First-in-Human Natural Killer Cell Combination Immunotherapy With Durable, Complete Response Data and 78% Disease Control in ...
NANTKWEST (NK)
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Source: Business Wire
World’s first combination of off-the-shelf NK with checkpoint inhibitor plus antigen simulation via adenovirus to induce immune system activationOngoing durable complete responses ranging from 8 to 11 months observed in TNBC patients who failed standard of careDisease control rate of 78% and overall response rate of 67% in heavily pretreated patientsMedian progression free survival exceeds 13 months compared to historical controls of 2-3 months in advanced third-line settingOngoing survival to date of 78% of patients ranging from 2 to 12 months CULVER CITY, Calif.--(BUSINESS WIRE)--NantKwest Inc. (Nasdaq: NK), a clinical-stage natural killer cell-based therapeutics company, and ImmunityBio, a privately held immunotherapy company, today announced results from their Phase 1b trial investigating a novel, first-in-human immunotherapy protocol consisting of NantKwest’s off-the-shelf, antibody-targeted NK cells (haNK) combined with ImmunityBio’s IL-15 superagonist (N-803), low-dose metro
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