Neoleukin Therapeutics Presents Preclinical Data on NEO-TRA1 at American Society of Hematology (ASH) Annual Meeting
Neoleukin Therapeutics, Inc. (NLTX)
Company Research
Source: GlobeNewswire
SEATTLE, Dec. 12, 2022 (GLOBE NEWSWIRE) -- Neoleukin Therapeutics, Inc., “Neoleukin” (NASDAQ:NLTX), a biopharmaceutical company utilizing sophisticated computational methods to design de novo protein therapeutics, today presented data on NEO-TRA1, a precision-tuned agonist of the IL-2 receptor beta and gamma subunits that is targeted to and selectively expands inhibitory T-regulatory cells. The data are being disclosed today as an oral presentation at the American Society of Hematology (ASH) Annual Meeting. The presentation highlights two important features of Neoleukin’s de novo protein technology: 1) the ability to target de novo cytokine mimetics to specific cell types, i.e. T-regulatory cells; and 2) precision-tuned de novo payloads that have minimal effects on non-targeted cells. By separating the targeting domain from the cytokine receptor agonist, Neoleukin scientists have created a potentially modular system for the cis-targeting of de novo proteins to specific immune cell
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