Neumora Therapeutics Announces Clinical Hold of Phase 1 NMRA-266 Study [Yahoo! Finance]
Neumora Therapeutics, Inc. (NMRA)
Company Research
Source: Yahoo! Finance
therapeutics pipeline consisting of seven clinical and pre-clinical brain disease programs, today announced that the Phase 1 trial of NMRA-266 has been placed on clinical hold by the U.S. Food and Drug Administration (FDA). NMRA-266 is a positive allosteric modulator (PAM) of the M4 muscarinic receptor and is part of the Company's M4 PAM franchise. The clinical hold determination follows recently available pre-clinical data showing convulsions in rabbits. Following this action, the Phase 1 single ascending dose / multiple ascending dose study with NMRA-266 has been paused. Approximately 30 participants have been dosed in the Phase 1 study, with no evidence of convulsions observed in any participant. Neumora is working with the FDA to evaluate the potential to resolve the clinical hold. While these discussions with the Agency are ongoing, the Company's prior guidance regarding NMRA-266 is no longer applicable. Neumora will provide an update on NMRA-266 when available. Neumora's M
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News
- Neumora Therapeutics Reports First Quarter 2024 Financial Results and Provides Business Update [Yahoo! Finance]Yahoo! Finance
- Neumora Therapeutics Reports First Quarter 2024 Financial Results and Provides Business UpdateGlobeNewswire
- Neumora Therapeutics to Participate in Upcoming Conferences in May [Yahoo! Finance]Yahoo! Finance
- Neumora Therapeutics to Participate in Upcoming Conferences in MayGlobeNewswire
- We're Hopeful That Neumora Therapeutics (NASDAQ:NMRA) Will Use Its Cash Wisely [Yahoo! Finance]Yahoo! Finance
NMRA
Earnings
- 3/7/24 - Miss
NMRA
Sec Filings
- 5/7/24 - Form 10-Q
- 5/7/24 - Form 8-K
- 4/25/24 - Form DEFA14A
- NMRA's page on the SEC website