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Stock impact report

Roche's (RHHBY) Combination Therapy Meets Goal in Lymphoma Study [Yahoo! Finance]

Nurix Therapeutics, Inc. - Common stock (NRIX) 
Company Research Source: Yahoo! Finance
oxaliplatin (GemOx), for the treatment of relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL) met its primary endpoint of overall survival. Columvi is Roche's fixed-duration and CD20xCD3 T-cell engaging bispecific antibody. It is currently approved as a monotherapy by the FDA to treat people with R/R DLBCL after two or more lines of systemic therapy on an accelerated basis. The drug has also received conditional marketing authorization in the EU for the same indication. The phase III STARGLO study results demonstrated that early-line R/R DLBCL patients, when treated with the Columvi/GemOx combination therapy, lived longer than those treated with MabThera/Rituxan (rituximab) in combination with GemOx. The study's secondary endpoints include progression-free survival, complete response rate (CRR), objective response rate and duration of objective response. Furthermore, Roche also stated that the safety profile of the investigational Columvi/GemOx combination thera Show less Read more
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