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Stock impact report

NTLA Stock Up More Than 6% as FDA Lifts ATTRv-PN Study Clinical Hold [Yahoo! Finance]

Intellia Therapeutics, Inc. (NTLA) 
Last intellia therapeutics, inc. earnings: 2/27 07:30 am Check Earnings Report
US:NASDAQ Investor Relations: ir.intelliatx.com/investor-overview
Company Research Source: Yahoo! Finance
study, MAGNITUDE-2, evaluating nexiguran ziclumeran (nex-z) in patients with hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PN). NTLA shares gained nearly 6.3% on Tuesday following the regulatory update. Over the past year, Intellia Therapeutics' shares have surged 46.6% compared with the industry's 17.2% rise. Image Source: Zacks Investment Research In October 2025, Intellia halted dosing and patient enrollment in its late-stage MAGNITUDE and MAGNITUDE-2 studies, which were evaluating nex-z for ATTR amyloidosis with cardiomyopathy (ATTR-CM) and ATTRv-PN, respectively. The studies were halted after a patient experienced grade 4 liver transaminase elevations and increased total bilirubin following dosing with nex-Z and later died. This triggered a clinical hold by the FDA on the IND and raised widespread concerns about the safety and future of the program. Intellia has aligned with the FDA on specific study modifications and risk-mitigation measures for M Show less Read more
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