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Neurotrope's Bryostatin Is Unlikely To Produce Significant Cognitive Efficacy [Seeking Alpha]

NextTrip, Inc. (NTRP) 
Company Research Source: Seeking Alpha
Neurotrope's Bryostatin Is Unlikely To Produce Significant Cognitive Efficacy Summary Extensive research by Neurotrope affiliated researchers indicate that Neurotrope's bryostatin 1 could improve cognition. Bryostatin 1 activates multiple PKC isozymes. These isozymes have different substrates in different cells types, which when activated may have both positive and negative effects on cognition. The scientific rationale for the confirmatory trial is weak, indicating that bryostatin 1's negative effects prevailed in the first phase 2, which makes the confirmatory trial outcome predictable. After thorough in-depth research, the balance of bryostatin 1's effects suggests that bryostatin 1's potential is limited, reducing Neurotrope's value significantly. Neurotrope Inc. (NASDAQ: NTRP An initial phase 2 result showed that the 20 ug bryostatin group improved on the Severe Impairment Battery (SIB) test compared to the placebo group (1-tailed test, p = 0.07, at week 13). However, using a 1-t Show less Read more
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