Novo GLP-1 drug shows less lean mass loss than rivals, study says [USA TODAY]
Novo Nordisk A/S (NVO)
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Source: USA TODAY
Eli Lilly's LLY.N GLP-1 drug tirzepatide yields greater weight loss on average than Novo Nordisk's NOVOb.CO semaglutide, but at a greater expense to muscles and connective tissues, according to a study published this week ahead of peer review. Tirzepatide, sold as Zepbound and Mounjaro, and semaglutide, under the brand names Wegovy and Ozempic, have become wildly popular for weight loss and have demonstrated other health benefits, such as heart-protective properties. But there has been concern that they induce loss of muscle and other components of lean body mass along with fat. The researchers analyzed data on roughly 1,800 patients using tirzepatide and 6,200 using semaglutide. Tirzepatide was consistently associated with greater loss of lean body mass than semaglutide. Tirzepatide patients lost an average of 1.1% more lean body mass after three months and 2% after 12 months of continuous use, the analysis by Massachusetts-based data analytics firm nference found. "This sug
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NVO
News
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- Kailera makes history with record-breaking $625m IPO [Yahoo! Finance]Yahoo! Finance
- Eli Lilly Weight-Loss Pill Prescriptions Near 1,400 in First Week [Yahoo! Finance]Yahoo! Finance
- Lilly's Foundayo hits 1,390 prescriptions in debut week [Yahoo! Finance Canada]Yahoo! Finance Canada
NVO
Earnings
- 2/3/26 - Beat
NVO
Sec Filings
- 4/13/26 - Form 6-K
- 4/7/26 - Form 6-K
- 3/30/26 - Form 6-K
- NVO's page on the SEC website