Vect-Horus Publication in Pharmaceutics Outlines How Vectors Can Improve Delivery of Therapeutics to Organs and Tumors [Yahoo! Finance]
Novo Nordisk A/S (NVO)
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Source: Yahoo! Finance
targeted delivery of therapeutic molecules and imaging agents, today announced the publication of a paper in the open-access scientific journal Pharmaceutics Vol 26 (MDPI). The paper, entitled “LDLR-Mediated Targeting and Productive Uptake of siRNA-Peptide Ligand Conjugates In Vitro and In Vivo”, outlines a study which showed how peptides developed by the company, that target the low-density lipoprotein receptor (LDLR) can support delivery of a model short interfering RNA (siRNA), both in vitro and in vivo . Because the LDLR is differentially expressed in organs and is overexpressed in many cancers including glioblastoma multiforme (GBM) and pancreatic ductal adenocarcinoma (PDAC), the results open new opportunities for delivery to different organs or tumors. A vector belonging to this family of LDLR-targeting peptides is applied as a theragnostic agent for the diagnostic of GBM and PDAC. The agent, currently in early Phase 1 clinical trials, is co-developed with RadioMedix. “Th
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Earnings
- 5/3/24 - Beat
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Sec Filings
- 5/2/24 - Form 6-K
- 5/1/24 - Form 6-K
- 4/26/24 - Form 6-K
- NVO's page on the SEC website