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Stock impact report

JPM26: Vor Bio narrows focus to two-indication strategy [Yahoo! Finance]

Novartis AG (NVS) 
Last novartis ag earnings: 4/28 01:00 am Check Earnings Report
US:NYSE Investor Relations: novartis.com/investors
Company Research Source: Yahoo! Finance
therapy to telitacicept, a dual BAFF/APRIL in-licensed from China-based Remegen in mid-2025. CEO Jean-Paul Kress, MD, emphasised that telitacicept has been clinically validated across more than eight autoimmune indications in China, and has a consistent safety profile, with over ten thousand patients treated commercially, creating a robust dataset for global expansion. The most notable strategic choice is prioritising myasthenia gravis (MG) and Sjögren's disease as lead indications while deprioritising lupus despite prior China approvals. Lupus has become increasingly crowded with multiple approved biologics, including GSK's Benlysta (belimumab), a BLyS/BAFF antagonist similar to telitacicept. Evolving treatment standards emphasising sustained durability and steroid-sparing effects have raised the bar for new entrants. This pivot positions the company in less saturated indications where mechanistic differentiation may translate more readily into commercial value. MG, by contrast, Show less Read more
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