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0 0.00775193798449613 0.0232558139534884 0.0232558139534884 0 0.0116279069767443 0.0154651162790699 0.00193798449612399
Stock impact report

OPKO Announces Positive Topline Results In Phase 2 Diabetes And Obesity Trial

Opko Health, Inc. (OPK) 
Last opko health, inc. earnings: 2/26 04:05 pm Check Earnings Report
US:NYSE Investor Relations: investor.opko.com
Company Research Source: GlobeNewswire
MIAMI, March 21, 2019 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) today announced positive topline results from a Phase 2 dose escalation trial of OPK88003 to treat type 2 diabetes and obesity.  OPK88003 is a once-weekly injectable oxyntomodulin compound with glucagon-like-peptide 1 (GLP-1) and glucagon dual agonist activity.  Based on data from a previous 420 patient Phase 2 study, an optimized dosing regimen for OPK88003 was evaluated to improve glucose control and increase weight loss.  Topline analysis of results of the study demonstrated that OPK88003 met the primary objective with a statistically significant lowering of hemoglobin A1c (HbA1c) after 30 weeks of treatment versus placebo as well as an important secondary endpoint, statistically significant weight loss versus placebo. This Phase 2b trial evaluated the effects of a dose escalation regimen of OPK88003 on HbA1c, weight loss and safety over 30 weeks in adult type 2 diabetes patients with inadequate glucose co Show less Read more
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