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Oruka Therapeutics: ORKA-001 For Psoriasis In Focus As 2026 Phase 2 Data Nears [Seeking Alpha]

Oruka Therapeutics, Inc. (ORKA) 
Company Research Source: Seeking Alpha
ORKA-001 could offer significant clinical benefits with only 1 to 2 doses per year. Its Phase 1 suggests a ~100-day half-life. But interestingly, it's possible that higher exposure may drive higher clearance and potential off-treatment remission. ORKA-002 could also deliver deeper efficacy via dual IL-17A/F neutralization with 2 to 3 doses per year. It also taps ORKA into PsA/HS. Lastly, ORKA has a highly liquid balance sheet and trades at reasonable valuation multiples. So, I feel it's a “Buy” at these levels. Catherine Delahaye/DigitalVision via Getty Images Oruka Therapeutics, Inc. ( ORKA ) is an early-stage immunology company that develops therapies for psoriasis and related diseases. ORKA's pipeline contains the biologics ORKA-001 for plaque psoriasis (PsO) and ORKA-002 for PsO, psoriatic arthritis (PsA) and hidradenitis suppurativa (HS). These candidates are designed to have improved efficiency and This article was written by Analyst's Disclosure: I/we have no sto Show less Read more
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