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Stock impact report

Palisade Bio: Gut Prodrug For IBD With Catalysts [Seeking Alpha]

Palisade Bio, Inc. (PALI) 
Company Research Source: Seeking Alpha
The main target indications are UC and FSCD, which promise a sizable TAM if PALI-2108 ultimately succeeds. Naturally, this means PALI's story remains early-stage and highly data-dependent. Yet, they have a compelling near-term catalyst stack. PALI's recent October 2025 raise also materially improved their cash runway and liquidity. Using those numbers, its valuation looks compelling relative to its peers. Thus, I lean towards a speculative "Buy" rating on PALI. PeopleImages/iStock via Getty Images Palisade Bio ( PALI ) is a clinical-stage biopharmaceutical firm focused on developing PALI-2108. This is a prodrug candidate studied for two IBD indications, ulcerative colitis (UC) and fibrostenotic Crohn's disease (FSCD), which both have significant unmet medical needs. PALI-2108 differentiates itself from other This article was written by Analyst's Disclosure: I/we have no stock, option or similar derivative position in any of the companies mentioned, and no plans to initi Show less Read more
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