Palisade Bio Receives Health Canada Clearance for Phase 1b Trial of PALI-2108 in Fibrostenotic Crohn’s Disease (FSCD)
Palisade Bio, Inc. (PALI)
Company Research
Source: GlobeNewswire
First dual-acting anti-inflammatory and anti-fibrotic candidate in development for FSCD, a condition with no approved therapies Patient dosing expected to commence in H2 2025; Topline data anticipated in Q1 2026 Continued progress toward Phase 2 IND submissions in Q1 2026 Carlsbad, CA, Sept. 05, 2025 (GLOBE NEWSWIRE) -- Palisade Bio, Inc. (Nasdaq: PALI) (“Palisade,” “Palisade Bio,” or the “Company”), a clinical-stage biopharmaceutical company developing precision therapies for autoimmune, inflammatory, and fibrotic diseases, today announced that it received a No Objection Letter ("NOL") from Health Canada for its Clinical Trial Application to evaluate PALI-2108, a first-in-class, ileocolonic-targeted PDE4 B/D inhibitor, in a Phase 1b clinical study for the treatment of fibrostenotic Crohn’s disease (FSCD). Up to half of Crohn’s disease patients develop FSCD over the course of their illness, and there are currently no approved anti-fibrotic therapies. Current standards of care—in
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PALI
News
- Palisade Bio Strengthens Clinical Leadership Team with Appointment of James Izanec, MD, AGAF as Vice President, Clinical DevelopmentGlobeNewswire
- Palisade Bio to Present at the Piper Sandler 37th Annual Healthcare ConferenceGlobeNewswire
- Individual investors are Palisade Bio, Inc.'s (NASDAQ:PALI) biggest owners and were rewarded after market cap rose by US$70m last week [Yahoo! Finance]Yahoo! Finance
- Palisade Bio (NASDAQ:PALI) had its "buy" rating reaffirmed by analysts at Citigroup Inc..MarketBeat
- Palisade Bio Appoints Sharon Skare as Vice President, Global Head of Clinical OperationsGlobeNewswire
PALI
Analyst Actions
- 11/11/25 - Citigroup Inc.
PALI
Sec Filings
- 12/4/25 - Form 8-K
- 11/12/25 - Form S-8
- 11/10/25 - Form 10-Q
- PALI's page on the SEC website