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-0.00162227930241987 0.0815195349466 -0.00229822901176142 -0.0400838177639583 -0.186156549952683 -0.153846153846154 -0.219683655536028 -0.196971745302149
Stock impact report

Palisade Bio Reports Positive PALI-2108 Phase 1b Clinical Data

Palisade Bio, Inc. (PALI) 
Company Research Source: GlobeNewswire
PALI-2108 demonstrated favorable safety, with no serious adverse events, lab abnormalities, or EKG concerns Phase 1b data demonstrated 100% clinical response and promising signals regarding the efficacy of PALI-2108 in ulcerative colitis (UC) using FDA-defined endpoints Biomarker analyses showed normalization of 186 genes linked to fibrosis and Crohn’s disease strictures, supporting translational potential in fibrostenotic Crohn’s disease (FSCD) Patient dosing in the Phase 1b FSCD study is expected to begin in 2H 2025; Phase 2 IND submissions anticipated in 1H 2026 Carlsbad, CA, Sept. 17, 2025 (GLOBE NEWSWIRE) -- Palisade Bio, Inc. (Nasdaq: PALI) (“Palisade,” “Palisade Bio,” or the “Company”), a clinical-stage biopharmaceutical company developing precision therapies for autoimmune, inflammatory, and fibrotic diseases, today announced new data from its ongoing clinical program evaluating PALI-2108, a first-in-class, ileocolonic-targeted PDE4 B/D inhibitor. The results are to be p Show less Read more
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