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-0.00202898550724625 -0.00207039337474116 -0.00621118012422347 -0.00828157349896481 -0.00828157349896481 0 0.00836438923395445 0.00828157349896481
Stock impact report

Wolfe Highlights Differentiation Potential in Palisade Bio, Inc. (PALI) Clinical Profile [Yahoo! Finance]

Palisade Bio, Inc. (PALI) 
Company Research Source: Yahoo! Finance
TheFly reported on April 8 that Wolfe Research initiated coverage of PALI with an Outperform rating and a $7 price target. The firm expects limited near-term activity in 2026 but maintains a constructive long-term view. It points to upcoming ulcerative colitis data expected in the second half of 2027 as a key catalyst, noting that the company's mechanism and internal analyses support a positive outlook despite mixed results seen in similar drug classes. The firm's view is based on the potential for the program's clinical profile to differentiate over time as additional data become available. Earlier on March 30, Palisade Bio, Inc. (NASDAQ:PALI) reported early-stage results from its Phase 1b study of PALI-2108 in patients with fibrostenotic Crohn's disease. The oral PDE4 prodrug showed a favorable safety profile with no serious adverse events and only mild, self-limiting side effects. Pharmacokinetic findings supported once-daily dosing with adequate systemic and gut tissue exposure Show less Read more
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