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Stock impact report

Puma Biotechnology Stock Declines More Than 9% in a Month: Here's Why [Yahoo! Finance]

Puma Biotechnology Inc (PBYI) 
Last puma biotechnology inc earnings: 2/20 04:07 pm Check Earnings Report
US:NYSE Investor Relations: pumabiotechnology.com/ir.html
Company Research Source: Yahoo! Finance
Shares of Puma Biotechnology PBYI have tanked 9.6% in the past month, reflecting the growing investor concern regarding the company's soft 2026 revenue outlook. The company's sole marketed product, Nerlynx (neratinib), is approved for treating early-stage HER2-positive breast cancer in patients previously treated with Roche 's RHHBY Herceptin-based adjuvant therapy. Nerlynx is also approved in combination with Xeloda (capecitabine) for treating advanced or metastatic HER2-positive breast cancer patients who have received two or more prior anti-HER2-based regimens in the metastatic setting. Nerlynx sales currently comprise the majority of PBYI's top line. Sales of the drug increased 4.6% year over year to $204.1 million in 2025. Despite the increasing sales for Nerlynx, Puma Biotechnology issued a weaker-than-expected 2026 financial outlook last month. This can be attributed to the primary reason for the stock's decline in the past month. PBYI's 2026 Outlook Muted & Pipeline U Show less Read more
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