PepGen Announces Highest Mean Splicing Correction Reported in DM1 Patients [Yahoo! Finance]
PepGen Inc. (PEPG)
Company Research
Source: Yahoo! Finance
– PGN-EDODM1 was generally well-tolerated at 15 mg/kg, with drug-related adverse events mild or moderate in severity – BOSTON, September 24, 2025 BUSINESS WIRE )--PepGen Inc. (Nasdaq: PEPG), a clinical-stage biotechnology company developing the next generation of oligonucleotide therapies with the goal of transforming the treatment of severe neuromuscular and neurological diseases, announced positive clinical data today from the 15 mg/kg dose cohort of its ongoing FREEDOM-DM1 Phase 1 single ascending dose (SAD) study in patients with myotonic dystrophy type 1 (DM1). These latest results demonstrated a mean splicing correction of 53.7% following a single 15 mg/kg dose of PGN-EDODM1, substantially higher than any previously reported splicing correction in DM1 patients. "We are delighted to report that the FREEDOM clinical study achieved all of its key objectives, including unprecedented splicing correction following a single dose of PGN-EDODM1 at 15 mg/kg," said Paul Streck, MD, MB
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News
- PepGen Inc.'s (NASDAQ:PEPG) largest shareholders are individual investors with 39% ownership, private equity firms own 36% [Yahoo! Finance]Yahoo! Finance
- PepGen (NASDAQ:PEPG) was upgraded by analysts at <a style="font-weight:bold" href="https://www.wallstreetzen.com/newsletters/zen-ratings?ticker=PEPG&utm_campaign=getratings&utm_medium=online&utm_source=MarketBeat">Wall Street Zen</a> froMarketBeat
- PepGen (NASDAQ:PEPG) had its price target raised by analysts at HC Wainwright from $18.00 to $20.00. They now have a "buy" rating on the stock.MarketBeat
- PepGen GAAP EPS of -$0.52 [Seeking Alpha]Seeking Alpha
- PepGen Reports Third Quarter 2025 Financial Results and Recent Corporate Highlights [Yahoo! Finance]Yahoo! Finance
PEPG
Earnings
- 11/12/25 - Beat
PEPG
Sec Filings
- 11/14/25 - Form SCHEDULE
- 11/12/25 - Form 8-K
- 11/12/25 - Form 10-Q
- PEPG's page on the SEC website