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Stock impact report

Pfizer (PFE) Announces Positive Phase 2b Results for Obesity Drug Showing 12.30% Weight Loss [Yahoo! Finance]

Pfizer, Inc. (PFE) 
Last pfizer, inc. earnings: 4/28 06:45 am Check Earnings Report
Company Research Source: Yahoo! Finance
Phase 2b VESPER-3 study of PF-08653944 (MET-097i), which is an injectable GLP-1 receptor agonist. The trial met its primary endpoint and showed a statistically significant, placebo-adjusted weight loss of up to 12.3% at 28 weeks. Notably, patients continued to lose weight after transitioning from weekly to monthly dosing, with no plateau observed by the end of the 28 weeks. The study also confirmed a favorable safety and tolerability profile, consistent with the broader GLP-1 class, as gastrointestinal side effects were primarily mild to moderate. These results have reinforced Pfizer's confidence in pursuing higher maintenance doses for its upcoming clinical trials. Detailed findings from the study are scheduled to be presented at the American Diabetes Association's Scientific Sessions in June 2026. Piotr Kowalski/Shutterstock.com Following its acquisition of Metsera, Pfizer is accelerating an expansive obesity development program that includes over 20 planned or ongoing studies Show less Read more
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