Pfizer Pauses Gene Therapy Trial for Muscle Disease After Death [BNN Bloomberg (Canada)]
Pfizer, Inc. (PFE)
Last pfizer, inc. earnings: 4/28 06:45 am
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Source: BNN Bloomberg
The patient, a young boy, suffered a cardiac arrest after receiving Pfizer's one-time treatment last year, the company said in an email. The boy was part of a mid-stage study, now concluded, that enrolled children between the ages of 2 and 4, the company said. Pfizer has paused administering the same gene therapy in a separate, final-stage study while it investigates the boy's death, the company said. That study is looking at the gene therapy, called fordadistrogene movaparvovec, to treat Duchenne muscular dystrophy, a rare and fatal muscle-wasting disease that primarily affects boys. Pfizer said it's working to “evaluate our investigational gene therapy while protecting the safety of the participants, which is our top priority.” The final-stage trial enrolled boys between the ages of 4 and 8, testing whether the therapy could slow disease progression compared to a placebo. Results from that study are expected this year. A competing gene therapy from Sarepta Therapeutics Inc.
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