Researchers identify immune trigger behind myocarditis after Covid vaccination [Los Angeles Times (CA)]
Pfizer, Inc. (PFE)
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Source: Los Angeles Times
found, shedding light on a mechanism that's fueled scientific debate and political controversy since the pandemic. The condition, myocarditis, appears most often in adolescent males and young men. It typically begins one to three days after a second vaccine dose, bringing on chest pain, shortness of breath or palpitations. Symptoms usually resolve quickly with supportive care — monitoring, rest and basic treatment to ease inflammation while the heart recovers on its own. The new research, published in Science Translational Medicine, traces the reaction to a sequential surge of inflammatory signals. It begins with the immune system's earliest sentinels — cells that act as first responders against infection. The scientists found that these cells, known as macrophages, release a wave of a signaling protein after an mRNA shot made by Pfizer Inc. and its partner BioNTech SE or by Moderna Inc. The burst prompts T cells, another branch of the immune system, to produce the protein inter
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