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0.213395638629283 0.261682242990654 0.270093457943925 0.363084112149533 0.465031152647975 0.328504672897196 0.331308411214953 0.308411214953271
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Intratumoral Injection of Phio’s PH-762 significantly inhibits tumor growth in murine tumor models and may generate memory-specific T cells

Phio Pharmaceuticals Corp. (PHIO) 
Last phio pharmaceuticals corp. earnings: 11/12 07:45 am Check Earnings Report
Company Research Source: GlobeNewswire
-Injection in murine tumors shows the compound is well tolerated -Studies support ongoing clinical trial of PH-762 as a neoadjuvant therapy for treatment of cSCC, melanoma, or Merkel cell carcinoma MARLBOROUGH, Mass., April 22, 2024 (GLOBE NEWSWIRE) -- Phio Pharmaceuticals Corp. (Nasdaq: PHIO), a clinical stage biotechnology company whose proprietary INTASYL™ siRNA gene silencing technology is designed to make immune cells more effective in killing tumor cells, today announced it is presenting new data about its lead clinical product candidate, PH-762, an INTASYL compound. Preclinical studies demonstrate: PH-762 is rapidly taken up by cells and robustly silences PD-1 mRNA and protein in lymphocytes within the tumor microenvironment (TME)Intratumoral injection of murine PH-762 (mPH-762) significantly inhibits tumor growth in murine tumor models and is well toleratedmPH-762-mediated silencing of PH-762 within the TME may generate memory-specific T cells, promoting IFN-? release in Show less Read more
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