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Stock impact report

Pliant Therapeutics Pivots to Oncology, Highlights Early PLN-101095 Responses at Oppenheimer Conference [Yahoo! Finance]

Pliant Therapeutics, Inc. (PLRX) 
Company Research Source: Yahoo! Finance
company, advancing internal oncology programs and a targeted siRNA delivery platform while evaluating potential in-licensing or acquisition opportunities. Early Phase I data for oral PLN-101095 (avß8/avß1 inhibitor) showed activity at =1,000 mg BID with four clinical responders (three PRs, one CR across four tumor types), an average tumor reduction of ~71% among responders, and generally manageable safety (most common AE: mild–moderate rash). Pliant plans a Phase Ib dose-expansion with pembrolizumab (first patient expected in Q2) across selected cohorts (NSCLC, high TMB, RCC), expects oncology data next year, and reported approximately $211 million pro forma cash supporting a runway into at least H2 2028. Interested in Pliant Therapeutics, Inc.? Here are five stocks we like better. Pliant Therapeutics Gaps 34% Higher: More Upside To Come? Pliant Therapeutics (NASDAQ:PLRX) used its presentation at Oppenheimer's 36th Annual Healthcare Conference to outline its strategic transi Show less Read more
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