Purple Biotech Reaches Recommended Phase 2 Dose for NT219 [Yahoo! Finance]
Purple Biotech Ltd. - American Depositary Shares (PPBT)
Company Research
Source: Yahoo! Finance
company developing first-in-class therapies that harness the power of the tumor microenvironment to overcome tumor immune evasion and drug resistance, today announced it has determined 100mg/kg is the recommended Phase 2 dose (RP2D) for NT219 in combination with cetuximab in the treatment of head and neck cancer based on its Phase 1/2 dose escalation study (NCT04474470). NT219 is a first-in-class small molecule dual inhibitor of IRS1/2 and STAT3. The RP2D was determined based on data from the open-label dose escalation study designed to assess the safety, pharmacokinetics, pharmacodynamics and efficacy of NT219 in combination with Erbitux® (cetuximab), in previously treated recurrent and/or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) patients. The Company recently reported that NT219, in combination with cetuximab, demonstrated a dose dependent anti-tumor activity with confirmed partial responses. No dose-limiting toxicities were reported. The additional su
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News
- Purple Biotech Ltd. (NASDAQ: PPBT) had its "buy" rating re-affirmed by analysts at HC Wainwright. They now have a $10.00 price target on the stock.MarketBeat
- Purple Biotech's Randomized Phase 2 CM24 Pancreatic Cancer Study Selected as Late-Breaking Abstract Poster Presentation at ASCO 2024 Annual Meeting [Yahoo! Finance]Yahoo! Finance
- Purple Biotech's Randomized Phase 2 CM24 Pancreatic Cancer Study Selected as Late-Breaking Abstract Poster Presentation at ASCO 2024 Annual MeetingGlobeNewswire
- Purple Biotech to Present New Data On its Oncology Drug NT219 at AACR 2024 [Yahoo! Finance]Yahoo! Finance
- Purple Biotech to Present New Data On its Oncology Drug NT219 at AACR 2024GlobeNewswire
PPBT
Sec Filings
- 4/25/24 - Form 6-K
- 4/3/24 - Form EFFECT
- 3/28/24 - Form POS
- PPBT's page on the SEC website