Prelude Therapeutics: Scientifically Interesting Oncology Company With Preclinical Data [Seeking Alpha]
Prelude Therapeutics Incorporated (PRLD)
Company Research
Source: Seeking Alpha
The company's current lead candidates are PRT3789, a SMARCA2 inhibitor, and PRT2527, a CDK9 inhibitor, both in phase 1 trials. Both programs have early preclinical data and look scientifically interesting. However, they are too early to merit an investment right now, although they bear watching. Prelude Therapeutics ( NASDAQ: PRLD ) is an early stage developer of cancer therapeutics. In 2022, their lead candidate, and the one program with efficacy data, used to be PRT811. PRT811 is a PRMT5 inhibitor which ran a phase 1 trial in solid tumors, including glioma and splicing mutated uveal melanoma, where it saw some positive data. This data was as follows: In the Phase 1 trials for PRT543 and PRT811, both molecules were generally well tolerated. In the PRT811 clinical trial, a total of 82 patients across multiple tumor types were enrolled in dose escalation and expansion, of whom 57 had glioma or uveal melanoma. Out of 38 glioma patients (16 IDH+ and 22 IDH-), two complete respon
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News
- Prelude Therapeutics Reports First Quarter 2024 Financial Results and Provides Corporate Update [Yahoo! Finance]Yahoo! Finance
- Prelude Therapeutics Reports First Quarter 2024 Financial Results and Provides Corporate UpdateGlobeNewswire
- Several Insiders Invested In Prelude Therapeutics Flagging Positive News [Yahoo! Finance]Yahoo! Finance
- Prelude Highlights Continued Strength of Discovery Engine at 2024 AACR Annual Meeting [Yahoo! Finance]Yahoo! Finance
- Prelude Highlights Continued Strength of Discovery Engine at 2024 AACR Annual MeetingGlobeNewswire
PRLD
Earnings
- 8/3/23 - Beat
PRLD
Sec Filings
- 5/7/24 - Form 10-Q
- 5/7/24 - Form 8-K
- 5/6/24 - Form S-3/A
- PRLD's page on the SEC website