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0 0.00034014657225031 -0.00290670707195628 -0.00275209499366086 -0.00290670707195628 -0.00584433655957204 -0.00708123318593646 -0.0157395095704875
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UniQure's AMT-060 shows treatment benefit in hemophilia B patients with pre-existing neutralizing antibodies; shares up 3% [Seeking Alpha]

uniQure N.V. - Ordinary Shares (QURE) 
Last uniqure n.v. - ordinary shares earnings: 4/29 07:00 am Check Earnings Report
US:NASDAQ Investor Relations: uniqure.com/investors-newsroom/overview.php
Company Research Source: Seeking Alpha
UniQure's AMT-060 shows treatment benefit in hemophilia B patients with pre-existing neutralizing antibodies; shares up 3%Are-analysis of pretreatment blood samples from a Phase 1/2 clinical trial assessing uniQure's (QURE+2.7%) AAV5 gene therapy AMT-060 in hemophilia B found that patients with pre-existing anti-AAV5 neutralizing antibodies still experienced a treatment benefit. The data were presented at ASGCT in Chicago.CSO Sander van Deventer, M.D., Ph.D., says, “These important data presented at ASGCT bolster our confidence that AAV5 gene therapies can provide successful liver transduction in all or nearly all patients. The study suggests that, in contrast to experience with other AAV vectors, detectable pre-existing neutralizing antibodies do not prevent successful gene transfer using AAV5 at clinical doses. In patients pre-exposed to AAV5 who tested positive for anti-AAV5 antibodies, therapeutic transgene expression was established with no cellular immune response observed after Show less Read more
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