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Stock impact report

Ultragenyx (RARE) Shares Positive Results From DTX301 Phase 3 Study [Yahoo! Finance]

Ultragenyx Pharmaceutical Inc. (RARE) 
Last ultragenyx pharmaceutical inc. earnings: 2/13 04:01 pm Check Earnings Report
US:NASDAQ Investor Relations: ir.ultragenyx.com/investor-relations
Company Research Source: Yahoo! Finance
On March 12, Ultragenyx Pharmaceutical Inc. (NASDAQ:RARE) announced that the Phase 3 Enh3ance study of DTX301, an experimental AAV8 gene therapy for the treatment of ornithine transcarbamylase deficiency, yielded favourable findings. Pressmaster/Shutterstock.com DTX301-treated patients showed a statistically significant and clinically meaningful 18% decrease in 24-hour plasma ammonia compared to placebo at Week 36 of the randomised, double-blind, placebo-controlled phase of the trial. Throughout Week 36, the average ammonia AUC0-24 remained within the normal range. Despite appropriate current medication treatment and dietary restriction, eight out of nine patients with abnormal ammonia AUC0-24 at baseline quickly reached normal ammonia levels, which were often maintained during this treatment period. On March 12, JPMorgan reduced its price target on Ultragenyx Pharmaceutical Inc. (NASDAQ:RARE) from $120 to $74. The firm maintained an Overweight rating on the shares. JPMorgan Show less Read more
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