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0 -0.000283586986137596 -0.000528250268295556 0.000550492384855348 -0.00154026657176696 0.00300824626471447 0.0093138863094212 0.0149411417990535
Stock impact report

Adverum Biotechnologies a new buy at H.C. Wainwright on wet AMD gene therapy [Seeking Alpha]

Regeneron Pharmaceuticals, Inc. (REGN) 
Last regeneron pharmaceuticals, inc. earnings: 2/6 06:30 am Check Earnings Report
US:NASDAQ Investor Relations: investor.regeneron.com
Company Research Source: Seeking Alpha
soroparvovec (lxo-vec), could become an alternative to the current standard of care, anti-vascular endothelial growth factor (anti-VEGF) injections. The firm has a $30 price target (~209% upside based on Tuesday's close). Analyst Matthew Caufield noted that wet AMD has a prevalence of ~1.5M patients in the U.S. with ~200,000 new cases annually. While these patients rely on anti-VEGF for treatment currently, they have to be given as often as every four to eight weeks, leading to chronic treatment burden and non-compliance. An interim analysis of 26-week phase 2 data found that patients given either dose of lxo-vec saw 90% and 94%, respectively, reductions in annualized anti-VEGF injections. Also, a phase 1 trial showed that one lxo-vec treatment led to aflibercept protein expression maintained through three years. "Ixo-vec utilizes a propriety vector capsid, AAV.7m8, carrying an aflibercept coding sequence under the control of a proprietary expression cassette," according to Show less Read more
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