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-0.00377675199328577 -0.00503566932438107 -0.0123793537557701 -0.0100713386487621 -0.0335711288292069 -0.0264372639530004 -0.0318925723877466 -0.0365086026017625
Stock impact report

Regenxbio raised to Buy at RBC on pivot to Duchenne [Seeking Alpha]

REGENXBIO Inc. (RGNX) 
Last regenxbio inc. earnings: 2/26 04:05 pm Check Earnings Report
US:NASDAQ Investor Relations: ir.regenxbio.com
Company Research Source: Seeking Alpha
Perform, arguing that the company's foray into Duchenne muscular dystrophy should drive further upside in its stock. The upgrade comes days after the Rockville, Maryland-based biotech updated interim data from its Phase 1/2 trial for gene therapy candidate RGX-202 in children with Duchenne muscular dystrophy early this week. At the time, the company said that the treatment targeted at the C-Terminal (CT) domain of disease-causing dystrophin protein led to a significant increase in microdystrophin expression in a 12-year-old patient. Regenxbio ( RGNX ) intends to use microdystrophin expression as a surrogate endpoint in seeking accelerated approval for RGX-202 in a future biologics license application (BLA) submission. “Data is early, and quintessential question of whether retaining the CT domain can drive better outcomes remains TBD, but expression data is impressive,” RBC analyst Luca Issi wrote, raising his price target to $35 from $20. The analyst argued that the upcoming Show less Read more
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