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0.000570939194975672 0.0134170710819297 -0.0094204967170997 -0.000713673993719749 -0.0222666286040538 -0.0550956323151586 -0.0582357978875251 -0.0538110191264631
Stock impact report

TransCode Therapeutics and Akribion Genomics Report Progress Developing CRISPR-Derived Technology for Cancer Treatment [Yahoo! Finance]

TransCode Therapeutics, Inc. (RNAZ) 
Company Research Source: Yahoo! Finance
treating cancer using RNA therapeutics, reported positive proof-of-concept laboratory studies in human cells, advancing its strategic partnership with Akribion Genomics. Akribion Genomics, a German-based biotechnology start-up, is focused on a CRISPR-derived molecular complex for cancer treatment. TransCode and Akribion are collaborating to develop a technology that combines Akribion's cell-killing G-dase E, a Class 2 CRISPR nuclease, with TransCode's TTX nucleic acid delivery platform. G-dase E has shown encouraging in vitro results in cells but requires an effective delivery vehicle, such as TTX, to reach intended targets in the body. Proof-of-concept studies to date suggest that Akribion's G-dase E ribonucleoprotein complexes could be conjugated to TransCode's TTX delivery platform, suggesting that the drug candidate could be formulated as intended. These studies also indicate that TTX-G-dase E ribonucleoprotein complexes could be taken up by cancer cells, inducing cancer cell Show less Read more
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