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0.000426439232409297 0.0028997867803837 0.00511727078891247 0.00597014925373122 0.000426439232409297 -0.00597014925373137 -0.0081023454157783 -0.00511727078891262
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Roivant Sciences Subsidiary Pulmovant Publishes Positive Phase 1 Data for Inhaled PH Treatment Mosliciguat [Yahoo! Finance]

Roivant Sciences Ltd. (ROIV) 
Company Research Source: Yahoo! Finance
publication of Phase 1 pharmacokinetic/PK data for inhaled mosliciguat in healthy male volunteers. The peer-reviewed manuscript, titled “Pharmacokinetics and Lung Deposition After Administration of Inhaled Mosliciguat (BAY 1237592): Results from Randomized Phase I Studies in Healthy Men,” was published in the journal Clinical Pharmacokinetics. The findings support the potential for once-daily inhaled administration of mosliciguat as a treatment option for patients with pulmonary hypertension/PH, suggesting a longer half-life compared to oral and IV administration, which could lead to limited systemic side effects. The published manuscript details three Phase 1 studies that characterized the PK profile of mosliciguat following inhalation via a low-resistance device using a lactose carrier-based dry powder formulation. A research scientist in a lab coat examining a sample of blood for sickle cell diseases. In all three studies, mosliciguat was well tolerated, with no major systemi Show less Read more
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