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Stock impact report

Revolution Medicines to Present Preclinical Data on Innovative Mutant-Targeted Catalytic RAS(ON) Inhibitor at the 2026 AACR Annual Meeting

Revolution Medicines, Inc. (RVMD) 
Company Research Source: GlobeNewswire
REDWOOD CITY, Calif., April 21, 2026 (GLOBE NEWSWIRE) -- Revolution Medicines, Inc. (Nasdaq: RVMD), a late-stage clinical oncology company developing targeted therapies for patients with RAS-addicted cancers, today announced preclinical data highlighting an innovative new class of mutant-targeted catalytic RAS(ON) inhibitors. These catalytic inhibitors are designed to promote the conversion of mutant RAS in its active RAS(ON) state back to the inactive RAS(OFF) state thereby mimicking the physiological regulation of wild type RAS. This mechanism represents a differentiated approach to inhibition of oncogenic RAS signaling with the goal of addressing tumor resistance mechanisms and extending the durability of current RAS-targeted therapies. Results will be presented during a mini symposium at the American Association for Cancer Research (AACR) Annual Meeting on April 21, 2026 (Abstract #6782). “Additional strategies are needed to counter emergent resistance to RAS inhibitors and fu Show less Read more
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