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Stock impact report

Rhythm Pharmaceuticals, Inc. Q4 2025 Earnings Call Summary [Yahoo! Finance]

Rhythm Pharmaceuticals, Inc. (RYTM) 
Last rhythm pharmaceuticals, inc. earnings: 3/8 08:12 am Check Earnings Report
US:NASDAQ Investor Relations: ir.rhythmtx.com
Company Research Source: Yahoo! Finance
Rhythm Pharmaceuticals, Inc. Q4 2025 Earnings Call Summary - Moby Strategic Execution and Commercial Momentum Full-year 2025 revenue reached $194.8 million, an increase of approximately 50% from 2024, driven by a 10% global increase in patients on reimbursed therapy and steady growth in international markets. Management attributed the 12% sequential revenue increase—growing from $51.3 million in Q3 to $57.3 million in Q4—to a 10% global rise in patients on reimbursed therapy, which was partially offset by a negative $1.3 million inventory swing at U.S. specialty pharmacies. The U.S. sales force expansion from 16 to 42 personnel is complete, focusing on identifying approximately 10,000 potential Acquired HO patients ahead of the March 20th PDUFA date. Phase 2 bivamelagon data in HO demonstrated BMI reductions of 14.3% at 40 weeks for the 600mg cohort, reinforcing the drug's potential as a potent oral alternative to setmelanotide. Strategic positioning in Japan is accelerat Show less Read more
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