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Stock impact report

SAB Biotherapeutics Pitches SAB-142 as Redosable Human ATG for Type 1 Diabetes at Oppenheimer Conf [Yahoo! Finance]

SAB Biotherapeutics, Inc. (SABS) 
Company Research Source: Yahoo! Finance
preserving regulatory T cells to preserve pancreatic beta cells, and SAB says it is redosable and avoids the serum sickness, anti-drug antibodies and ADCC-driven lymphodepletion seen with rabbit ATG. The global Phase IIb SAFEGUARD trial targets newly diagnosed Stage 3 T1D patients (ages 5–40) with 2.5 mg/kg, 1.5 mg/kg and placebo arms dosed every six months, uses 1-year C-peptide as the primary endpoint, is considered by the company and FDA to be pivotal, and plans last patient in by end-2026 with top-line data in H2 2027. SAB ended 2025 with $140 million in cash, which management says funds SAFEGUARD through top-line readout plus about one additional year into 2028, while citing an initial U.S. addressable market of ~64,000 new Stage 3 diagnoses per year and using Tzield's ~$200,000 price as a commercial reference. Interested in SAB Biotherapeutics, Inc.? Here are five stocks we like better. Promising Upsides on these Biotech Penny Stocks SAB Biotherapeutics (NASDAQ:SABS) u Show less Read more
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