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-0.000381097560975669 -0.000381097560975669 0.00266768292682928 0.000381097560975534 -0.000754573170731709 0.00952743902439024 0.000762195121951203 -0.00114329268292687
Stock impact report

Sage (SAGE) Down 20% on Parkinson's Study Missing Primary Goal [Yahoo! Finance]

Sage Therapeutics, Inc. (SAGE) 
Last sage therapeutics, inc. earnings: 2/27 06:30 am Check Earnings Report
US:NASDAQ Investor Relations: investor.sagerx.com/investor-relations
Company Research Source: Yahoo! Finance
its lead neuropsychiatric candidate dalzanemdor in patients with mild cognitive impairment (MCI) associated with Parkinson's disease (PD). The study failed to achieve its primary endpoint of demonstrating a statistically significant difference from baseline in participants treated with orally-administered dalzanemdor, when compared to placebo. Per management, the analyses of data also did not indicate any meaningful differences versus placebo in the other exploratory endpoints, such as SCOPA-Cog. Management also pointed out that 48 patients, which represent more than half of the total study participants, experienced treatment emergent adverse events (TEAEs) ranging from mild to moderate in severity. Based on these results, management has decided not to pursue the development of dalzanemdor in PD indication. The share price was down likely due to this reason. Year to date, shares of Sage have lost 42.0% compared with the industry's 11.2% fall. Image Source: Zacks Investment R Show less Read more
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