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Stock impact report

Lexeo Therapeutics: Only Smallcap Gene Therapy For Alzheimer's [Seeking Alpha]

Sangamo Therapeutics, Inc. (SGMO) 
Last sangamo therapeutics, inc. earnings: 2/28 07:00 am Check Earnings Report
US:NASDAQ Investor Relations: investor.sangamo.com
Company Research Source: Seeking Alpha
LX1001 targets APOE4 homozygous patients with Alzheimer's disease by delivering a functional APOE2 gene using the AAVrh10 vector. Its other product, LX2006, targets FA cardiomyopathy using the same vector. Lexeo ( NASDAQ: LXEO ) is a small company and recent IPO which according to Evaluate has the rare distinction of getting the first gene therapy targeting Alzheimer's into the clinic - meaning in human trials. This is not exactly true; there have been a few other gene therapies targeting Alzheimer's in the clinic. But that does not reduce its achievement much; Lexeo is still one of a very few select companies with gene therapy programs in the clinic. It is also the only small company in the list. A few other such gene therapy trials: An April 2023 phase 1 trial sponsored and undertaken by UCL and UCLH uses a “gene silencing” approach using BIIB080 (/IONIS-MAPTRx) to target the gene coding for the tau protein production process. This asset, or a version of it, is now in phase Show less Read more
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