Silence Therapeutics Announces Positive Topline 36-Week Data from Ongoing Phase 2 Study of Zerlasiran in Patients with High Lipoprotein(a)
Silence Therapeutics Plc - American Depository Share (SLN)
Company Research
Source: Business Wire
Study met primary endpoint and demonstrated highly significant reductions in Lp(a) to week 36Lipoprotein(a) reduction was consistent with phase 1 resultsTopline 48-week data expected in 2Q 2024 LONDON--(BUSINESS WIRE)--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or the “Company”), an experienced and innovative biotechnology company committed to transforming people’s lives by silencing diseases through precision engineered medicines, today announced positive topline 36-week data from the ongoing ALPACAR-360 phase 2 study of zerlasiran (SLN360) in 178 subjects with baseline lipoprotein(a), or Lp(a), levels at or over 125 nmol/L at high risk of atherosclerotic cardiovascular disease (ASCVD) events. Zerlasiran is a siRNA (short interfering RNA) designed to lower the body’s production of Lp(a), a key genetic risk factor for cardiovascular disease affecting up to 20% of the world’s population.In the double-blind placebo-controlled treatment period, zerlasiran was administered at 300
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News
- Silence Therapeutics plc (NASDAQ: SLN) had its "overweight" rating re-affirmed by analysts at Morgan Stanley. They now have a $45.00 price target on the stock.MarketBeat
- Silence Therapeutics (SLN) Surges 5.7%: Is This an Indication of Further Gains? [Yahoo! Finance]Yahoo! Finance
- Silence Therapeutics Announces JAMA Publication of Additional Phase 1 Data for Zerlasiran in Subjects with Elevated Lipoprotein(a) [Yahoo! Finance]Yahoo! Finance
- Silence Therapeutics Announces JAMA Publication of Additional Phase 1 Data for Zerlasiran in Subjects with Elevated Lipoprotein(a)Business Wire
- Silence Therapeutics plc (NASDAQ: SLN) had its price target raised by analysts at Chardan Capital from $26.00 to $42.00. They now have a "buy" rating on the stock.MarketBeat
SLN
Sec Filings
- 4/15/24 - Form 6-K
- 3/27/24 - Form SC
- 3/13/24 - Form 20-F
- SLN's page on the SEC website