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Stock impact report

Soleno Therapeutics, Inc. Q4 2025 Earnings Call Summary [Yahoo! Finance]

Soleno Therapeutics, Inc. (SLNO) 
Last soleno therapeutics, inc. earnings: 5/13 08:00 am Check Earnings Report
US:NASDAQ Investor Relations: investors.soleno.life/investor-overview
Company Research Source: Yahoo! Finance
Soleno Therapeutics, Inc. Q4 2025 Earnings Call Summary - Moby Commercial Execution and Strategic Positioning Achieved full-year profitability and positive cash flow within nine months of the VYKAT XR launch, driven by strong adoption in the PWS market. Captured approximately 12.5% of the addressable U.S. market by year-end, with 859 patients on active treatment and 1,250 total start forms received. Attributed durable growth to high prescriber engagement, with 630 unique prescribers and significant utilization across both pediatric and adult (ages 27-45) populations. Maintained a real-world safety profile consistent with clinical trials, reporting a 12% discontinuation rate due to adverse events against a total discontinuation rate of 15%. Secured broad payer coverage for over 180 million lives, with management noting that the reauthorization process has been efficient due to recognized unmet need in hyperphagia. Strategic expansion beyond PWS is focused on Glycogen Sto Show less Read more
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