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Stock impact report

SNGX: Positive Results for Phase 2a Trial in Psoriasis [Yahoo! Finance]

Soligenix, Inc. (SNGX) 
NASDAQ:AMEX Investor Relations: soligenix.com/investors
Company Research Source: Yahoo! Finance
On December 17, 2025, Soligenix, Inc. (NASDAQ:SNGX) announced positive results from Cohort 3 of its ongoing Phase 2a trial of SGX302 (synthetic hypericin) for the treatment of mild-to-moderate psoriasis. Cohort 3 consisted of four patients who were enrolled and treated with an improved topical gel formulation of synthetic hypericin. The gel formulation was designed to improve the patient experience as it is easier to dispense and apply to the skin. The patients were treated for 18 weeks, similar to patients in Cohort 1 and 2. For the three evaluable patients (one patient discontinued for personal reasons), noted improvements were seen in the Investigator Global Assessment (IGA), the Psoriasis Activity and Severity Index (PASI), the simplified psoriasis index, the dermatology life quality index and the Skindex-29 questionnaire. Importantly, one patient achieved a disease status of “Almost Clear” using the IGA and a 50% improvement in PASI score. Looking at the totality of the data gen Show less Read more
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